• Thyroid Hormone Nuclear Receptor. Methods and Protocols [Gebundene Ausgabe]
  • Thyroid Hormone Nuclear Receptor. Methods and Protocols [Gebundene Ausgabe]

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    EAN / ISBN-139781493979011
    Höhe25.4 cm
    ProduktformGebundene Ausgabe
    Auflage1st edition 2019
    Seitenanzahl300
    HerausgeberSpringer US
    Erscheinungsdatum 2018
    Inhaltsverzeichnis1. Thyroid Hormone Receptors: Several Players for One Hormone and Multiple Functions Jacques Samarut and Michelina Plateroti   2. Two Protocols to Study the Interactions of Thyroid Hormone Receptors with Other Proteins and Chromatin Wenyue Guan, Romain Guyot, and Frédéric Flamant   3. Expression Analysis of Genes Regulated by Thyroid Hormone in Neural Cells Juan Bernal and Beatriz Morte 4. In vitro Approaches to Identify Thyroid Hormone Receptor-dependent Transcriptional Response Maria Sirakov and Michelina Plateroti   5. Posttranslational Modification of Thyroid Hormone Nuclear Receptor by Phosphorylation Yan-Yun Liu and Gregory A. Brent   6. Posttranslational Modification of Thyroid Hormone Nuclear Receptor by Sumoylation Yan-Yun Liu and Gregory A. Brent   7. Demonstration of the Receptor Site for Thyroid Hormone on Integrin αvβ3 Hung-Yun Lin, Shaker A. Mousa, and Paul J Davis   8. The Deiodinase Trio a nd Thyroid Hormone Signaling Antonio C. Bianco and Rodrigo R. da Conceição   9. Thyroid Hormones and Derivatives – Endogenous Thyroid Hormones and their Targets Josef Köhrle   10. Protocols for Studying how Thyroid Hormone Receptors Trigger Adaptive Thermogenesis in Mice Karine Gauthier   11. Pharmacological Inhibition of Lysosomal Activity as a Method For Monitoring Thyroid Hormone-induced Autophagic Flux in Mammalian Cells in vitro Jin Zhou, Rohit A. Sinha, Ronny Lesmana, Winifred WY. Yau, and Paul M. Yen   12. Analysis of Physiological Responses to Thyroid Hormones and their Receptors in Bone J.H. Duncan Bassett and Graham R. Williams   13. Evaluating the Hypothalamic-Pituitary-Thyroid (HPT) Axis in Mice FE Wondisford   14. Thyroid Hormone Action: The p43 Mitochondrial Pathway Chantal Wrutniak-Cabello, François Casas, and Gérard Cabello   15. Evaluating thyroid Disrupting Chemicals in vivo using Xenopus laevis Bilal B. Mughal, Barbara A Demeneix, and Jean-Baptiste Fini   16. Quantification of Thyromimetic Sobetirome Concentration in Biological Tissue Samples Jordan Devereaux, Skylar J. Ferrara, and Thomas S. Scanlan   17. Analysis of Thyroid Tumorigenesis in Xenograft Mouse Model Xuguang Zhu and Sheue-yann Cheng   18. Human Genetics Of Thyroid Hormone Receptor Beta: Resistance to thyroid Hormone Beta Theodora Pappa and Samuel Refetoff   19. TRa Mutations in Human Briet C, Bouhours-Nouet Natacha, Illouz F, Prunier-Mirebeau D, and  Rodien P   20. Role of Thyroid Hormone Receptor in Amphibian Development Liezhen Fu, Luan Wen, and Yun-Bo Shi   21. de novo Transcriptomic Approach To Study Thyroid Hormone Receptor Action in Non-mammalian Models Nicolas Buisine, Gwenneg Kerdivel, and Laurent M. Sachs   22. Role of TRs in Zebrafish Development Federica Marelli and Luca Persani  
    HauptbeschreibungThis volume aims to detail the advances in the field of Thyroid hormones (THs), namely T3 and T4, and their nuclear receptor TRs from a conceptual and methodological point of view. Chapters guide readers through a general introduction, TR's engineered mice, human genetics of TRs, control of the hypothalamus-pituitary-thyroid (HPT) axis, the relevance of the local THs production and metabolism and pathological consequences of TH/TR alterations. Non-mammalian models are also presented and discussed. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.   Authoritative and practical, Thyroid Hormone Nuclear Receptor: Methods and Protocols aims to ensure successful results in the further study of this vital field.
    Breite17.8 cm
    SpracheEnglisch

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