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Bücher Englische Bücher Wissen & Bildung Naturwissenschaft, Medizin, Informatik, Technik Biologie Mikrobiologie The Th2 Type Immune Response in Health and Disease
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The Th2 Type Immune Response in Health and Disease
(Gebundene Ausgabe, Englisch)
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Beschreibung
The type 2 immune response that develops during infectious disease has undergone major paradigm shifts in the last several years as new cell types and pathways have been identified. It is now clear that the type 2 immune response, characterized by elevations in specific cytokines, including IL-4, IL-5 and IL-13, is associated with helminth infections in both humans and mice. This response is… complex and includes effector functions that mediate resistance, contributing to expulsion and in some cases destruction, of the parasite. But just as importantly, the type 2 immune response can also mediate tolerance mechanisms, which can mitigate tissue injury as these large multicellular parasites transit through vital organs. The tolerance mechanisms include both tissue repair and immune regulatory effects. These latter aspects of the helminth-induced type 2 immune response are increasingly recognized as a potential resource that can be mined for the development of novel immunotherapies that may enhance wound healing, control of autoimmune and inflammatory diseases and regulation of metabolic homeostasis. In this book, leading researchers in this exciting and dynamic field discuss the latest findings and emerging concepts, providing an intellectual framework that can be used as a basis for new discoveries and potentially new treatments for diseases associated with inflammation. Dieses Produkt haben wir gerade leider nicht auf Lager.
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Technische Daten
Erscheinungsdatum
25.11.2015
Sprache
Englisch
EAN
9781493929108, 9781493929108
Herausgeber
Springer US
Sonderedition
Nein
Seitenanzahl
172
Auflage
1
Einbandart
Gebundene Ausgabe
Buch Untertitel
From Host Defense and Allergy to Metabolic Homeostasis and Beyond
Schlagwörter
Helminth, Immune response, Parasites, Th2 type immune response, inflammation
Thema-Inhalt
PSG - Mikrobiologie (nicht-medizinisch)
MJCM - Immunologie
MKFM - Mikrobiologie und Virologie
Höhe
235 mm
Breite
15.5 cm
Transparenz & Sicherheit
Hersteller: Springer, Europaplatz 3, Heidelberg, Deutschland, 69115, ProductSafety@springernature.com, Springer Nature Customer Service Center GmbH
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