Enantioselective Synthesis of Beta-Amino Acids

20.05.2005

Englisch

9780471467380, 9780471467380

John Wiley & Sons

Nein

634

2

Gebundene Ausgabe

EUSEBIO JUARISTI is currently Professor of Chemistry at Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Mexico. The author of seven chemistry books, Dr. Juaristi received the Mexican Academy of Sciences Award for Young Scientists in 1988, and the Inter-American Science and Technology Prize of the Organization of American States in 1990. More recently, in 1998, he received the Presidential Medal, the highest recognition for Mexican scientists. VADIM SOLOSHONOK is a professor in the Department of Chemistry and Biochemistry at the University of Oklahoma.

Asymmetrische Synthese, Aminosäuren

Preface. Preface to the First Edition. Contributors. 1. Structural Types of Relevant b-Amino Acid Targets (Eusebio Juaristi). 2. beta-Amino Acids in Natural Products (Peter Spiteller and Franz von Nussbaum). 3. Preparation of Enantiopure beta-Amino Acids by Homologation of alpha-Amino Acids (Joachim Podlech). 4. Asymmetric Catalysis in Enantioselective Synthesis of beta-Amino Acids (Anna G. Wenzel and Eric N. Jacobsen). 5. Enantioselective Synthesis of Conformationally Constrained beta-Amino Acids (Rosa M. Ortuño). 6. Catalytic Enantioselective Mannich Reactions (Masaharu Ueno and Shu Kobayashi). 7. Enantioselective Synthesis of beta-Amino Acids via Stereoselective Hydrogenation of beta-Aminoacrylic Acid Derivatives (Eusebio Juaristi, Vctor Manuel Gutiérrez-Garca, and Heraclio López-Ruiz) 8. Asymmetric Synthesis of beta-Amino Acids by Enolate Additions to tert-Butanesulfinyl Imines (Kristin Brinner and Jonathan A. Ellman). 9. Organocatalytic Approaches to Enantioenriched beta-Amino Acids (Fujie Tanaka and Carlos F. Barbas, III). 10. Asymmetric Synthesis of Cyclic beta-Amino Acids via Cycloaddition Reactions (José Barluenga, Bernardo Olano, Josefa Flórez, and Carlos Valdés). 11. Enantioselective Synthesis of Novel beta-Amino Acids (Javed Iqbal and Saibal Kumar Das). 12. Asymmetric Synthesis of Phosphonic Analogs of beta-Amino Acids (Marian MikoBajczyk, Józef Drabowicz, and Piotr Lyzwa). 13. Asymmetric Synthesis of alpha-Substituted-beta-Amino Phosphonates and Phosphinates and beta-Amino Sulfur Analogs (Francisco Palacios, Concepción Alonso, and Jesús de los Santos). 14. Stereoselective Synthesis of Fluorine-Containing beta-Amino Acids (Santos Fustero, Juan F. Sanz-Cervera, and Vadim A. Soloshonok). 15. Enantioselective Synthesis of beta-Amino Acids via Conjugate Addition to alpha, beta-Unsaturated Carbonyl Compounds (Scott J. Miller and David J. Guerin). 16. Preparation of Enantiopure beta-Amino Acids via Enantioselective Conjugate Addition (Mei Liu and Mukund P. Sibi). 17. Biocatalytic Entry to Enantiomerically Pure beta-Amino Acids (Dmitrii O. Berbasov, Trevor K. Ellis, and Vadim A. Soloshonok). 18. Stereoselective Synthesis of beta-Amino Acids via Radical Reactions (Takeaki Naito and Okiko Miyata). 19. Recent Advances in Synthesis of alpha-Hydroxy-beta-amino Acids and Their Use in SAR Studies of Taxane Anticancer Agents (Jin Chen, Larisa V. Kuznetsova, Ioana M. Ungreanu, and Iwao Ojima). 20. Synthesis of beta-Amino Acids and Their Derivatives from b-Lactams: Update (Claudio Palomo, Jesús M. Aizpurua, Iñaki Ganboa, and Mikel Oiarbide). 21. Multiple-Component Condensation Methods for Preparation of Combinatorial Libraries of beta-Amino Carbonyl Derivatives (James C. Adrian, Jr.). 22. Using Constrained b-Amino Acid Residues to Control beta-Peptide Shape and Function (Michael A. Gelman and Samuel H. Gellman). 23. beta2-Amino Acids with Proteinogenic Side Chains and Corresponding Peptides: Synthesis, Secondary Structure, and Biological Activity (Marino A. Campo, Jaime Escalante, and Radovan Scaron;ebesta). Abbreviations. References. Index.

242 mm

16 cm