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Bücher Englische Bücher Wissen & Bildung Naturwissenschaft, Medizin, Informatik, Technik Biologie Biochemie & Biophysik Role of Proteases in Cellular Dysfunction
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Role of Proteases in Cellular Dysfunction
(Taschenbuch, Englisch)
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Beschreibung
It is now well known that proteases are found everywhere, in viruses and bacteria as well as in all human, animal and plant cells, and play a role in a variety of biological functions ranging from digestion, fertilization, development to senescence and death. Under physiological conditions the ability of proteases is regulated by endogenous inhibitors. However, when the activity of proteases is… not regulated appropriately, disease processes can result, as seen in Alzheimer’s disease, cancer metastasis and tumor progression, inflammation and atherosclerosis. Thus it is evident that there is an absolute need for a tighter control of proteolytic activities in different cells and tissues. Aimed at graduate students and researchers with an interest in cellular proteolytic events, Role of Proteases in Cellular Dysfunctions is the second book on Proteases in this series. The book consists of three parts in specified topics based on current literatures for a better understanding for the readers with respect to their subject-wise interests. The first section of this book covers a brief idea about the neuronal disorders and the involvement of proteases such as calpains, caspases and matrix metalloproteases (MMPs). The second section covers the deadly disease cancer and its relation to ubiquitin-proteasome system, MMPs and serine proteases. The last section is about the role of proteases such as calpains, MMPs and serine protease as well as urokinase type plasminogen activator receptor (uPAR) in causing cardiovascular defects. 160,49 €
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Technische Daten
Erscheinungsdatum
23.08.2016
Sprache
Englisch
EAN
9781493946341
Herausgeber
Springer US
Serien- oder Bandtitel
Advances in Biochemistry in Health and Disease
Sonderedition
Nein
Seitenanzahl
462
Auflage
1
Einbandart
Taschenbuch
Bandzählung
8
Schlagwörter
antiproteases, cancer, cardiovascular diseases, cell dysfunction, diabetes, proteases, Proteomics, Receptors
Thema-Inhalt
PSB - Biochemie
PSF - Zellbiologie (Zytologie)
MJCL - Onkologie
PSAN - Neurowissenschaften
MBGR - Medizinische Forschung
Höhe
235 mm
Breite
15.5 cm
Transparenz & Sicherheit
Hersteller: Springer Nature Customer Service Center GmbH, Europaplatz 3, Heidelberg, Deutschland, 69115, ProductSafety@springernature.com
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