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Bücher Englische Bücher Wissen & Bildung Naturwissenschaft, Medizin, Informatik, Technik Biologie Genetik & Gentechnik Simple Mathematical Models of Gene Regulatory Dynamics
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Simple Mathematical Models of Gene Regulatory Dynamics
Michael C. Mackey, Moisés Santillán, Marta Tyran-Kamińska, Eduardo S. Zeron (Taschenbuch, Englisch)
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Beschreibung
This is a short and self-contained introduction to the field of mathematical modeling of gene-networks in bacteria. As an entry point to the field, we focus on the analysis of simple gene-network dynamics. The notes commence with an introduction to the deterministic modeling of gene-networks, with extensive reference to applicable results coming from dynamical systems theory. The second part of… the notes treats extensively several approaches to the study of gene-network dynamics in the presence of noise—either arising from low numbers of molecules involved, or due to noise external to the regulatory process. The third and final part of the notes gives a detailed treatment of three well studied and concrete examples of gene-network dynamics by considering the lactose operon, the tryptophan operon, and the lysis-lysogeny switch. The notes contain an index for easy location of particular topics as well as an extensive bibliography of the current literature. The target audience of these notes are mainly graduates students and young researchers with a solid mathematical background (calculus, ordinary differential equations, and probability theory at a minimum), as well as with basic notions of biochemistry, cell biology, and molecular biology. They are meant to serve as a readable and brief entry point into a field that is currently highly active, and will allow the reader to grasp the current state of research and so prepare them for defining and tackling new research problems. Dieses Produkt haben wir gerade leider nicht auf Lager.
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Technische Daten
Erscheinungsdatum
17.11.2016
Sprache
Englisch
EAN
9783319453170
Herausgeber
Springer International Publishing
Serien- oder Bandtitel
Lecture Notes on Mathematical Modelling in the Life Sciences
Sonderedition
Nein
Autor
Michael C. Mackey, Moisés Santillán, Marta Tyran-Kamińska, Eduardo S. Zeron
Seitenanzahl
124
Einbandart
Taschenbuch
Schlagwörter
92-XX, 37-XX, gene regulation, mathematical modeling, operon, dynamical systems, stochastic systems, gene expression, systems biology, ordinary differential equations
Thema-Inhalt
PSAK - Genetik (nicht-medizinisch)
PSAX - DV-gestützte Biologie/Bioinformatik
PBW - Angewandte Mathematik
PBKJ - Differentialrechnung und -gleichungen
PBT - Wahrscheinlichkeitsrechnung und Statistik
PBWL - Stochastik
Höhe
235 mm
Breite
15.5 cm
Hersteller: Springer Nature Customer Service Center GmbH, Europaplatz 3, Heidelberg, Deutschland, 69115, ProductSafety@springernature.com
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