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Bücher Englische Bücher Wissen & Bildung Naturwissenschaft, Medizin, Informatik, Technik Biologie Zoologie Statistical Mechanics, Protein Structure, and Protein Substrate Interactions
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Statistical Mechanics, Protein Structure, and Protein Substrate Interactions
(Taschenbuch, Englisch)
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Beschreibung
A number of factors have come together in the last couple of decades to define the emerging interdisciplinary field of structural molecular biology. First, there has been the considerable growth in our ability to obtain atomic-resolution structural data for biological molecules in general, and proteins in particular. This is a result of advances in technique, both in x-ray crystallography, driven… by the development of electronic detectors and of synchrotron radiation x-ray sources, and by the development ofNMR techniques which allow for inference of a three-dimensional structure of a protein in solution. Second, there has been the enormous development of techniques in DNA engineering which makes it possible to isolate and clone specific molecules of interest in sufficient quantities to enable structural measurements. In addition, the ability to mutate a given amino acid sequence at will has led to a new branch of biochemistry in which quantitative measurements can be made assessing the influence of a given amino acid on the function of a biological molecule. A third factor, resulting from the exponential increase in computing power available to researchers, has been the emergence of a growing body of people who can take the structural data and use it to build atomic-scale models of biomolecules in order to try and simulate their motions in an aqueous environment, thus helping to provide answers to one of the most basic questions of molecular biology: the relation of structure to function. 213,99 €
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Technische Daten
Erscheinungsdatum
19.06.2013
Sprache
Englisch
EAN
9781489913517
Herausgeber
Springer US
Serien- oder Bandtitel
NATO Science Series B:
Sonderedition
Nein
Seitenanzahl
406
Einbandart
Taschenbuch
Schlagwörter
Peptide, X-ray, development, mechanics, proteins
Thema-Inhalt
PSV - Zoologie und Tierwissenschaften
PHVN - Biophysik
Höhe
235 mm
Breite
15.5 cm
Transparenz & Sicherheit
Hersteller: Springer Nature Customer Service Center GmbH, Europaplatz 3, Heidelberg, Deutschland, 69115, ProductSafety@springernature.com
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