Chemical Synthesis of Hormones, Pheromones and Other Bioregulators

13.08.2010

Englisch

9780470697245

John Wiley & Sons

Nein

Kenji Mori

314

Gebundene Ausgabe

Biochemistry (Chemical Biology), Biochemie u. Chemische Biologie, Wirkstoffforschung u. -entwicklung, Naturstoffchemie, Organic Chemistry, Chemistry, Organische Chemie, Drug Discovery & Development, Chemie, Natural Products, Organische Synthese

PNN - Organische Chemie

Preface Abbreviations 1. Introduction - Biofunctional Molecules and Organic Synthesis 1.1 What are biofunctional molecules? 1.2 Developmental stages of studies on biofunctional molecules 1.3 Small amounts of the samples are now sufficient for the elucidation of the structures of biofunctional molecules 1.4 Why must biofunctional molecules be synthesized? 1.5 How can we synthesize biofunctional molecules? 1.6 What kinds of knowledge and techniques are necessary to synthesize biofunctional molecules? References 2. Synthesis of Phytohormones, Phytoalexins and Other Biofunctional Molecules of Plant Origin 2.1 Phytohormones 2.2 Phytoalexins 2.3 Plant allelochemicals 2.4 Other bioactive compounds of plant origin References 3. Synthesis of Insect Bioregulators other than Pheromones 3.1 Insect juvenile hormones 3.2 Insect antifeedants 3.3 Insect repellents References 4. Synthesis of Pheromones 4.1 What are pheromones? 4.2 Methods for enantioselective synthesis 4.3 Why is it meaningful to synthesize enantiopure pheromones ? 4.4 Chiral pheromones whose single enantiomers show bioactivity 4.5 Chiral pheromones whose stereochemistry-bioactivity relationships are diverse and complicated 4.6 Significance of chirality in pheromone science References 5. Synthesis of Biofunctional Molecules of Microbial Origin 5.1 Microbial hormones 5.2 Antibiotics 5.3 Other biofunctional molecules of microorganisms References 6. Synthesis of Marine Bioregulators, Medicinals and Related Compounds 6.1 Marine natural products of ecological importance such as antifeedants 6.2 Marine natural products of medicinal interest 6.3 Glycosphingolipids and sphingolipids of medical interests References 7. Synthetic Examination of Incorrectly Proposed Structures of Biomolecules 7.1 Origin of incorrect or obscure structures 7.2 Structure fabrications of historical interest 7.3 Incorrect structures resulting from inappropriate use of purification or analytical methods 7.4 Inappropriate structural proposal caused by problems in bioassay methods 7.5 Human errors are inevitable in chemistry, too References 8. Conclusion -- Science as a Human Endeavor 8.1 Small molecules are also beautiful 8.2 Continuous efforts may bring something meaningful 8.3 Can a scientist eventually have a hope in future? Acknowledgments Index

246 mm

18.9 cm