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Bücher Englische Bücher Wissen & Bildung Naturwissenschaft, Medizin, Informatik, Technik Medizin Vitamin C - Lipoprotein (a) - Cholesterol. Prof. Dr. Linus Pauling - Dr. Matthias Rath
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Vitamin C - Lipoprotein (a) - Cholesterol. Prof. Dr. Linus Pauling - Dr. Matthias Rath
Volker H. Schendel (Taschenbuch, Englisch)
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High Lp(a) in blood is a risk factor for coronary heart disease (CHD), cardiovascular disease (CVD), atherosclerosis, thrombosis, and stroke.[37] The association between Lp(a) levels and stroke is not as strong as that between Lp(a) and cardiovascular disease.[3] Lp-a concentrations may be affected by disease states (for example kidney failure), but are only slightly affected by diet, exercise,… and other environmental factors. Most commonly prescribed lipid-reducing drugs have little or no effect on Lp(a) concentration. Results using statin medications have been mixed in most trials, although a meta-analysis published in 2012 suggests that atorvastatin may be of benefit.[Niacin VitaminB3 (nicotinic acid) and aspirin are two relatively safe, easily available and inexpensive drugs known to significantly reduce the levels of Lp(a) in some individuals with high Lp(a); they should be used under the supervision of a qualified physician.[medical citation needed]
High Lp(a) predicts risk of early atherosclerosis independently of other cardiac risk factors, including LDL. In patients with advanced cardiovascular disease, Lp(a)indicates a coagulant risk of plaque thrombosis. Apo(a) contains domains that are very similar to plasminogen (PLG). Lp(a) accumulates in the vessel wall and inhibits binding of PLG to the cell surface, reducing plasmin generation, which increases clotting. This inhibition of PLG by Lp(a) also promotes proliferation of smooth muscle cells. These unique features of Lp(a) suggest Lp(a) causes generation of clots and atherosclerosis.
Vegetarians have higher levels of Lp-a than fish eaters in one homogeneous tribal population of Tanzania raising the possibility that pharmacologic amounts of fish oil supplements may be helpful to lower the levels of Lp-a.
Some studies have shown that regular consumption of moderate amounts of alcohol leads to significant decline in plasma levels of Lp-a while other studies have not. Dieses Produkt haben wir gerade leider nicht auf Lager.
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Technische Daten
Erscheinungsdatum
01.01.2017
Sprache
Englisch
EAN
9783743136649
Herausgeber
Books on Demand
Autor
Volker H. Schendel
Auflage
1
Einbandart
Taschenbuch
Höhe
215 mm
Breite
13.5 cm
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