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Bücher Englische Bücher Wissen & Bildung Naturwissenschaft, Medizin, Informatik, Technik Medizin Nichtklinische Fächer Mucosal Immune Defense: Immunoglobulin A
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Mucosal Immune Defense: Immunoglobulin A
(Gebundene Ausgabe, Englisch)
Optischer Zustand
Beschreibung
Immune responses at mucosal surfaces play a major role in host mucosal defense against microbial pathogens and in the pathogenesis of acute and chronic mucosal inflammatory diseases. This volume draws on a broad spectrum of molecular biologic, biochemical, and immunogenetic approaches in combination with human and murine in vitro cell culture and in vivo model systems to address questions in… mucosal immunity. Humans produce more immunoglobulin A (IgA) than all other antibody isotypes combined, most of which is rapidly transported into the external secretions bathing mucous membranes. It has been estimated that more than 3 grams of IgA are transported daily into mucosal secretions, carrying out a wide range of antimicrobial and anti-inflammatory functions. IgA is the second most abundant class of antibody in the bloodstream, contributing to systemic as well as secretory immunity. Recent advances in human genomics, gene regulation, structural biology, cell signaling, and immunobiology have greatly enhanced our understanding of this important class of antibody. This book is designed to serve as a concise reference of the present knowledge of the biology of IgA, including structure of IgA and its interaction with Fc receptors; epithelial transport of IgA; regulation of the mucosal IgA system; biological roles of IgA, including newly discovered functions; IgA-associated diseases, and therapeutic applications for IgA. Chapters have been contributed by internationally recognized leaders in the field of IgA research, representing 8 countries on 3 continents. Dieses Produkt haben wir gerade leider nicht auf Lager.
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Technische Daten
Erscheinungsdatum
04.10.2007
Sprache
Englisch
EAN
9780387722313
Herausgeber
Springer US
Sonderedition
Nein
Seitenanzahl
434
Auflage
2007
Einbandart
Gebundene Ausgabe
Einbandart Details
Fadenbindung
Schlagwörter
Antigen, antibody, antimicrobial, cell, cell culture, diseases, gene, gene regulation, immunobiology, immunoglobulin, pathogenesis, polymer, research, infectious diseases
Thema-Inhalt
MJCM - Immunologie
PSG - Mikrobiologie (nicht-medizinisch)
MJC - Krankheiten und Störungen
MKG - Pharmakologie
MJCM1 - Medizin: Allergien
Höhe
235 mm
Breite
15.6 cm
Transparenz & Sicherheit
Hersteller: Springer Us, ProductSafety@springernature.com, Springer Nature Customer Service Center GmbH
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