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Bücher Englische Bücher Wissen & Bildung Naturwissenschaft, Medizin, Informatik, Technik Biologie Biochemie & Biophysik Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems
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Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems
Marc Thiriet (Taschenbuch, Englisch)
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Beschreibung
The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological… conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to phenomenological models of nano- and microscopic events in a corrector scheme of regulated mechanisms when the vessel lumen caliber varies markedly. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. Volume 4 is devoted to major sets of intracellular mediators that transmit signals upon stimulation of cell-surface receptors. Activation of signaling effectors triggers the release of substances stored in cellular organelles and/or gene transcription and protein synthesis. Complex stages of cell signaling can be studied using proper mathematical models, once the role of each component is carefully handled. Volume 4 also reviews various categories of cytosolic and/or nuclear mediators and illustrates some major signal transduction pathways, such as NFkappaB axis, oxygen sensing, and mechanotransduction. Dieses Produkt haben wir gerade leider nicht auf Lager.
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Technische Daten
Erscheinungsdatum
23.08.2016
Sprache
Englisch
EAN
9781493952076
Herausgeber
Springer US
Serien- oder Bandtitel
Biomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems
Sonderedition
Nein
Autor
Marc Thiriet
Seitenanzahl
1064
Auflage
Softcover reprint of the original 1st edition 2013
Einbandart
Taschenbuch
Schlagwörter
blood flow behavior, blood flow prediction, cardiovascular systems modeling, cell signalling pathways, ion and molecule carriers described, modeling respiratory function, modeling simulation of flows, physiological flows, receptors ligands, signaling mediators explained, ventilatory systems modeling, Systems Biology
Thema-Inhalt
PHVN - Biophysik
MQW - Biomedizinische Technik
PSAX - DV-gestützte Biologie/Bioinformatik
TGMF - Maschinenbau: Strömungsmechanik
MJD - Kardiologie, Angiologie
Höhe
235 mm
Breite
15.5 cm
Hersteller: Springer Nature Customer Service Center GmbH, Europaplatz 3, Heidelberg, Deutschland, 69115, ProductSafety@springernature.com
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