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Bücher Englische Bücher Wissen & Bildung Naturwissenschaft, Medizin, Informatik, Technik Biologie Biochemie & Biophysik Regulation of Ca2+-ATPases,V-ATPases and F-ATPases
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Regulation of Ca2+-ATPases,V-ATPases and F-ATPases
(Taschenbuch, Englisch)
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Beschreibung
The biological membranes of cellular organization enfold an important group of membrane proteins called the ATPases, which are not only versatile in maintaining chemical gradient and electrical potential across the membrane but also bring metabolites necessary for cell metabolism and drive out toxins, waste products and solutes that otherwise can curb cell functions. ATPases are distributed… virtually in all live forms starting from unicellular to multicellular and also in viruses. There are different types of ATPases, which differ in function and structure and in the type of ions they transport. The three main types of the ion pump ATPase family are: (i) P-type ATPases that transport different ions across membranes and Ca 2+ ATPases belongs to this catagory (ii) F-type ATPase in mitochondria, chloroplasts and bacterial plasma membranes produce ATP using the proton gradient; and (iii) V-type ATPase catalyzes ATP hydrolysis to transport solutes and maintains acidic pH in organelles like lysosomes. Genetic defects in either of the ATPases cause several diseases and a number of researches have demonstrated the involvement of the members of ATPases in the cell pathology and diseases, thereby penetrating exciting new areas of our understanding. In this book, the authors summarize recent knowledge about the molecular mechanisms associated with Ca 2+ -ATPase, V-ATPase and F-ATPase in intracellular and extracellular Ca 2+ transport, mitochondrial ATP synthase, vesicular H + transport, and lysosomal pH regulation. This book thereby bridges the gap between fundamental research and biomedical and pharmaceutical applications. The book provides an informative resource to improve ATPase research and modern therapeutic approaches toward different life threatening diseases that are associated with dysregulation of the ATPases. Dieses Produkt haben wir gerade leider nicht auf Lager.
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Technische Daten
Erscheinungsdatum
27.03.2019
Sprache
Englisch
EAN
9783319796772
Herausgeber
Springer International Publishing
Serien- oder Bandtitel
Advances in Biochemistry in Health and Disease
Sonderedition
Nein
Seitenanzahl
586
Auflage
Softcover reprint of the original 1st edition 2016
Einbandart
Taschenbuch
Bandzählung
14
Schlagwörter
Ca2+-ATPases, F-ATPases, V-ATPases, (P)RR/ATP6ap2, Acid-base, Protein Structure
Thema-Inhalt
PSB - Biochemie
PSF - Zellbiologie (Zytologie)
PHN - Kernphysik
MBGR - Medizinische Forschung
Höhe
235 mm
Breite
15.5 cm
Hersteller: Birkhäuser, Europaplatz 3, Heidelberg, Deutschland, 69115, ProductSafety@springernature.com, Springer Nature Customer Service Center GmbH
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