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Bücher Englische Bücher Wissen & Bildung Naturwissenschaft, Medizin, Informatik, Technik Chemie Organische Chemie Synthesis of Functionalized Organoboron Compounds Through Copper(I) Catalysis
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Synthesis of Functionalized Organoboron Compounds Through Copper(I) Catalysis
Koji Kubota (Taschenbuch, Englisch)
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Beschreibung
This book describes state-of-the-art borylation chemistry using copper(I) catalysis. Enantioselective reactions are included to afford a variety of functionalized, complex organoboronate esters, which will find wide application in asymmetric synthesis, drug discovery, and material science. Organoboron compounds are recognized as useful reagents in organic synthesis; therefore, great effort has… been devoted to the development of a simple, mild, and efficient method for their preparation in the past several years. However, the synthesis of functionalized organoboron compounds remains a challenging issue because known reactions often require the use of highly reactive organometallic carbon nucleophiles. This book focuses on conceptually new, formal nucleophilic copper(I)-catalyzed borylation reactions with diboron compounds that show high selectivity and excellent functional group compatibility. Theoretical studies based on density functional theory calculations to understand the reactionmechanisms have also been described. Advances in this novel borylation chemistry will allow the rapid and efficient synthesis of complex molecules with potentially interesting properties in combination with the boron functionalization process. 106,99 €
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Technische Daten
Erscheinungsdatum
12.12.2018
Sprache
Englisch
EAN
9789811352713
Herausgeber
Springer Singapore
Serien- oder Bandtitel
Springer Theses
Sonderedition
Nein
Autor
Koji Kubota
Seitenanzahl
213
Auflage
Softcover reprint of the original 1st edition 2017
Einbandart
Taschenbuch
Schlagwörter
Organoboron compound, Enantioselective borylation, Nucleophilic borylation, Copper catalyst, Diboron compound
Thema-Inhalt
PNN - Organische Chemie
PNRD - Katalyse
Höhe
235 mm
Breite
15.5 cm
Hersteller: Springer, Europaplatz 3, Heidelberg, Deutschland, 69115, ProductSafety@springernature.com, Springer Nature Customer Service Center GmbH
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