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Bücher Englische Bücher Wissen & Bildung Naturwissenschaft, Medizin, Informatik, Technik Biologie Biochemie & Biophysik Dynamic Analysis of Enzyme Systems
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Dynamic Analysis of Enzyme Systems
Katsuya Hayashi, Naoto Sakamoto (Broschiert, Englisch)
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Beschreibung
This book is concerned with a quantitative analysis of dynamic behavior of various enzymatic reaction systems by computer simulation. The authors and coworkers have been engaged in cooperative research since 1975, seeking to clarify the catalytic and regulatory characteristics of enzymatic reactions in vivo and control mechanisms suitable for enzyme technology. Rather than "enzyme kinetics"… generally known in enzymol· ogy, this research has employed an approach called "enzyme dynamics" which concentrates on the exact schematic representation of an actual reac tion mechanism, derivation of rate equation on the basis of the scheme, and computer simulation of its dynamic behavior (numerical solution of the rate equation and explanation of kinetic and regulatory properties of the enzymatic reaction). A rate equation representing the behavior of enzymatic reactions is gen erally expressed by a set of nonlinear differential equations. The analytic solution of rate equations is therefore impossible in general, making it necessary to introduce some approximations in order to analyze the exper· imental data in enzyme kinetics. For example, under an assumption of excess substrate against enzyme in a closed system, we commonly use the linear approximation for the early period of reaction, the quasi-steady state approximation based on putative maintenance of steady state in en zyme species, and the rapid-equilibrium approximation assuming instantane ous equilibration in complex formation and between complexes. The kinetic characteristics obtained by these approximations do not always reflect the dynamic behavior of actual enzymatic reactions. Dieses Produkt haben wir gerade leider nicht auf Lager.
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Technische Daten
Erscheinungsdatum
09.01.2013
Sprache
Englisch
EAN
9783662115848
Herausgeber
Springer Berlin
Sonderedition
Nein
Autor
Katsuya Hayashi, Naoto Sakamoto
Seitenanzahl
370
Einbandart
Broschiert
Buch Untertitel
An Introduction
Schlagwörter
Analysis, Enzyme, Systems
Thema-Inhalt
PSB - Biochemie
MFG - Physiologie
Hersteller: Springer Nature Customer Service Center GmbH, Europaplatz 3, Heidelberg, Deutschland, 69115, ProductSafety@springernature.com
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