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Bücher Englische Bücher Wissen & Bildung Naturwissenschaft, Medizin, Informatik, Technik Medizin Nichtklinische Fächer 25 Years of p53 Research
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Beschreibung
1. Communication, awareness and access to information: Given the complexity of the field and the fact that data pertaining to each particular aspects of p53 biology or deregulation are scattered in many different publications, it is extremely difficult to access the full scale of relevant information of any specific p53-related topic. Review arcticles, despite their fundamental role in… disseminating knowledge, usually focus only on general mechanisms and do not discuss in detail the many variations that can occur with respect to cell type, particular mutation type, as well as biological activation context. Books such as this one may help in this task by putting into perspective both general considerations on the p53 pathway and more specific information on various aspects of p53. In the longer term, however, open access to p53 complexity will require the development of knowledge bases accessible through the web and using simple navigation tools to guide users towards the specific information they need. Several efforts are currently being developed in that direction. They need to be strenghtened and better integrated within the rapidly growing galaxy of web-based information sources on molecular and individual variations in cancer. 2. Reference functional assays and structural analysis: Given the huge diversity of cellular and animal models for wild-type or mutant p53 functions, it will be important to set up standard, universally accepted assays to measure critical p53 protein functions. Dieses Produkt haben wir gerade leider nicht auf Lager.
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Technische Daten
Erscheinungsdatum
18.04.2005
Sprache
Englisch
EAN
9781402029202
Herausgeber
Springer Netherland
Sonderedition
Nein
Seitenanzahl
446
Einbandart
Gebundene Ausgabe
Schlagwörter
DNA, P53, Wiman, Hainaut, tumor suppressor genes, apoptosis, muta, apoptosis, biology, cancer, cancer research, cancer therapy, cell, genes, molecular biology, mutagen, oncogene, protein, regulation, tumor
Thema-Inhalt
MJCL - Onkologie
MBGR - Medizinische Forschung
MJCM - Immunologie
PSA - Biowissenschaften, allgemein
Höhe
235 mm
Breite
15.5 cm
Transparenz & Sicherheit
Hersteller: Springer, Europaplatz 3, Heidelberg, Deutschland, 69115, ProductSafety@springernature.com, Springer Nature Customer Service Center GmbH
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