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Bücher Wissen & Bildung Englische Bücher Naturwissenschaft, Medizin, Informatik, Technik Medizin Nichtklinische Fächer Ionic and Volume Changes in the Microenvironment of Nerve and Receptor Cells
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Ionic and Volume Changes in the Microenvironment of Nerve and Receptor Cells
Eva Sykova (Broschiert, Englisch)
Optischer Zustand
Beschreibung
Stability of the internal environment in which neuronal elements are situated is unquestionably an important prerequisite for the effective transmission of information in the nervous system. During the past decade our knowledge on the microenvironment of nerve cells has expanded. The conception that the microenvironment of neurones comprises a fluid with a relatively simple and stable composition… is no longer accepted; the microenvironment is now envisaged as a dynamic structure whose composition, shape, and volume changes, thereby significantly influencing neuronal function and the trans mission of information in the nervous system. The modern conception of the neuronal microenvironment is based on the results of research over the last 20 years. The extracellular space (ECS) is comprehended not only as a relatively stable microenvironment containing neurones and glial cells (Bernard 1878), but also as a channel for communica tion between them. The close proximity of the neuronal elements in the CNS and the narrowness of the intercellular spaces provides a basis not only for interaction between the elements themselves, but also between the elements and their microenvironment. Substances which can cross the cell membranes can easily find their way through the microenvironment to adjacent cellular elements. In this way the microenvironment can assure non-synaptic com munication between the relevant neurones. Signalization can be coded by modulation of the chemical composition of the ECS in the vicinity of the cell membrane and does not require classic connection by axones, dendrites, and synapses. 106,99 €
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Technische Daten
Erscheinungsdatum
21.12.2011
Sprache
Englisch
EAN
9783642769399
Herausgeber
Springer Berlin
Serien- oder Bandtitel
Progress in Sensory Physiology
Sonderedition
Nein
Autor
Eva Sykova
Seitenanzahl
167
Auflage
1
Einbandart
Broschiert
Transparenz & Sicherheit
Hersteller: Springer Nature Customer Service Center GmbH, Europaplatz 3, Heidelberg, Deutschland, 69115, ProductSafety@springernature.com
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