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Beschreibung
In the last ten years there has been a considerable increase of interest on the notion of the minimal cell. With this term we usually mean a cell-like structure containing the minimal and sufficient number of components to be defined as alive, or at least capable of displaying some of the fundamental functions of a living cell. In fact, when we look at extant living cells we realize that thousands… of molecules are organized spatially and functionally in order to realize what we call cellular life. This fact elicits the question whether such huge complexity is a necessary condition for life, or a simpler molecular system can also be defined as alive. Obviously, the concept of minimal cell encompasses entire families of cells, from totally synthetic cells, to semi-synthetic ones, to primitive cell models, to simple biomimetic cellular systems. Typically, in the experimental approach to the construction of minimal the main ingredient is the compartment. Lipid vesicles (liposomes) are used to host simple and complex molecular transformations, from single or multiple enzymic reactions, to polymerase chain reactions, to gene expression. Today this research is seen as part of the broader scenario of synthetic biology but it is rooted in origins of life studies, because the construction of a minimal cell might provide biophysical insights into the origins of primitive cells, and the emergence of life on earth. The volume provides an overview of physical, biochemical and functional studies on minimal cells, with emphasis to experimental approaches. 15 International experts report on their innovative contributions to the construction of minimal cells. 160,49 €
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Technische Daten
Erscheinungsdatum
25.11.2014
Sprache
Englisch
EAN
9789401781589
Herausgeber
Springer Netherland
Sonderedition
Nein
Seitenanzahl
298
Auflage
1
Einbandart
Broschiert
Buch Untertitel
The Biophysics of Cell Compartment and the Origin of Cell Functionality
Schlagwörter
liposeomes (lipid vesicles), micro-compartmentation, origing of life, self-organization, synthetic biology, gene expression
Thema-Inhalt
MBGR - Medizinische Forschung
TCB - Biotechnologie
PSF - Zellbiologie (Zytologie)
PSAK - Genetik (nicht-medizinisch)
Höhe
235 mm
Breite
15.5 cm
Transparenz & Sicherheit
Hersteller: Springer, Europaplatz 3, Heidelberg, Deutschland, 69115, ProductSafety@springernature.com, Springer Nature Customer Service Center GmbH
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