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Bücher Englische Bücher Wissen & Bildung Naturwissenschaft, Medizin, Informatik, Technik Geowissenschaft Assay of Calcium-regulating Hormones
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Beschreibung
The ability to measure accurately the hormones regulating calcium homeosta sis is the fundamental first step toward understanding the roles these hormones play in health and disease. Techniques for such measurements have only been available for the past 10 years or so and remain in a state of rapid development. Sensitive parathyroid hormone (PTH) radioimmunoassays appeared in the early 1970s, and… with them came a whole new appreciation for the prevalence and implications of hyperparathyroidism, primary or secondary, in the popu lation. The calcitonin (CT) radioimmunoassay came later and achieved rapid success in the. diagnosis of a previously poorly understood cancer, medullary carcinoma of the thyroid, frequently associated with the familial multiple endo crine neoplasia type 2 syndromes (a and b). As the sensitivity of the calcitonin radioimmunoassay has improved, our understanding of the role of calcitonin in normal physiological processes has increased. The knowledge that vitamin D must be metabolized to produce its biologic effects is only 15 years old. This has had profound implications in our understanding of a variety of metabolic bone, kidney, and gastrointestinal diseases. Assays to measure the major cir culating form of vitamin D, 25-hydroxyvitamin D, were described 10 years ago. Assays for the other metabolites, in particular, 1,25-dihydroxyvitamin D, were described even more recently. As of today, we know of many vitamin D metabolites and have developed the techniques to measure most of them; how ever, many questions remain concerning their physiological role. 53,49 €
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Technische Daten
Erscheinungsdatum
10.10.2011
Sprache
Englisch
EAN
9781461255550
Herausgeber
Springer US
Sonderedition
Nein
Seitenanzahl
271
Einbandart
Broschiert
Schlagwörter
Assay, Calcium, Calzitonin, Hormones, Immunologie, Parathormon, Radioimmunologie, Vitamin D, bone, homeostasis, hormone, receptor, thyroid hormone
Thema-Inhalt
RN - Umwelt
MJG - Endokrinologie
MFG - Physiologie
PSB - Biochemie
MJ - Klinische und Innere Medizin
Höhe
235 mm
Breite
15.5 cm
Hersteller: Springer Nature Customer Service Center GmbH, Europaplatz 3, Heidelberg, Deutschland, 69115, ProductSafety@springernature.com
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