Label-free and Multi-parametric Monitoring of Cell-based Assays with Substrate-embedded Sensors

05.10.2017

Englisch

9783319453835

Springer International Publishing

Springer Theses

Nein

Maximilian Oberleitner

370

Gebundene Ausgabe

Maximilian Oberleitner was born in 1983 in Bavaria, Germany and graduated from the University of Regensburg with a Diploma in Chemistry in 2008. Based on this doctoral thesis “Label-free and Multi-parametric Monitoring of Cell-based Assays with Substrate-embedded Sensors” he obtained his PhD in Analytical Chemistry in 2016 in the Institute of Analytical Chemistry, Chemo- and Biosensors at the University of Regensburg under the supervision of Prof. Dr. Joachim Wegener. His research work was focused on the development and improvement of substrate-integrated sensors for the analysis of living cells. These sensors enable the monitoring of cell-substrate interactions and the real-time analysis of assays with adherently grown cells in a non-invasive, label-free and – by combinations of the different types of sensors – even in a multi-parametric manner. Since 2015 he works at a global healthcare company in Austria. As project leader in the quality unit he is responsible for stability studiesand quality evaluations of antibiotics.

Cell-based assays, Label-free high-content sensing, Quartz crystal microbalance, Impedance spectroscopy, Electric cell-substrate impedance sensing, Cytomechanic sensing, Confocal laser scanning microscopy, Optical temperature and oxygen imaging, Dynamic cell response, Biological recognition unit, Mulitparametric whole-cell biosensing, Fluorescence lifetime imaging, Cell culture

PNF - Analytische Chemie TBN - Nanotechnologie PDT - Nanowissenschaften MBGR - Medizinische Forschung PSF - Zellbiologie (Zytologie) PDN - Wissenschaftliche Ausstattung, Experimente und Techniken PHVN - Biophysik

235 mm

15.5 cm