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War in the Body
W David Wick, Otto O Yang (Gebundene Ausgabe, Englisch)
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Beschreibung
In the relatively few decades since the introduction of HIV into the human population, variants of the virus have diverged to such an extent that, were the discussion about something other than viruses, said variants could easily be classified as different species. This book will consider these evolutionary variations, as well as the different and, at times, opposing theories attempting to explain… them. It will compare and contrast the ways in which the immune system and drugs affect the virus's evolution, and the implications of these for vaccine development. The issue will be explored and explained through "ecological genetics," which postulates that all living organisms have, besides rivals, enemies. This is divergent from the more traditional school of "population genetics," which emphasizes that evolution occurs among rival species (or variants thereof) that compete for niches or resources in a fixed, unreactive environment. Both models will be formulated using mathematical models, which will be included in the book. Finally, it will consider the possibilities for designing a vaccine that blocks HIV from escaping the immune system. Dieses Produkt haben wir gerade leider nicht auf Lager.
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Technische Daten
Erscheinungsdatum
10.07.2013
Sprache
Englisch
EAN
9781461472933
Herausgeber
Springer US
Sonderedition
Nein
Autor
W David Wick, Otto O Yang
Seitenanzahl
298
Einbandart
Gebundene Ausgabe
Buch Untertitel
The Evolutionary Arms Race Between HIV and the Human Immune System and the Implications for Vaccines
Autorenporträt
Dr. Yang is a well known T-Cell and HIV expert at UCLA. Dr. Wick is recently retired. His last position was Senior Scientist in the Infectious Diseases Division of the Fred Hutchison Center, in Seattle, where he worked on immune response to HIV and vaccines.
Schlagwörter
Drug Resistance, HIV/AIDS, Viral Evolution, vaccines
Thema-Inhalt
PSG - Mikrobiologie (nicht-medizinisch)
MJCM - Immunologie
MKG - Pharmakologie
Höhe
235 mm
Breite
15.5 cm
Hersteller: Springer Nature Customer Service Center GmbH, Europaplatz 3, Heidelberg, Deutschland, 69115, ProductSafety@springernature.com
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