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Opioid Analgesics
A.F. Casy, R.T. Parfitt (Broschiert, Englisch)
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Beschreibung
The rapidly burgeoning research of the past two decades on agonist-antagonist analgesics and opioid receptors makes this exhaustive review of opioid anal gesics particularly relevant and timely. After an introductory chapter the additional 12 chapters begin logically with morphine and congeners (4- epoxymorphinans) and end with opioid receptors. All principal chemical types of centrally acting… analgesics (including endogenous opioid-like substances) and their antagonists as well as the mixed agonist-antagonists are treated thoroughly, although not always (and for good reason) in historical (chrono logical) order. A chapter on miscellaneous types (atypical structures for the most part) includes the benzimidazoles (etonitazene), aminotetralins (dezocine), tetrahydroisoquinolines (methopholine), and so on. Important aspects and correlations of chemistry, pharmacology, and biochemistry are discussed in depth. Literature citations are numerous. For educators, practicing laboratory scientists, and physicians, this scholarly review by two authors well of opioid analgesics versed in the chemistry, pharmacology, and biochemistry will be informative, stimulating, and thought-provoking. Everette L. May Medical College of Virginia Richmond, VA 23298 v Preface The history of opium predates the written word, although knowledge of its constituents dates back less than 200 years. Over the centuries its popularity for the relief of pain has waxed and waned, until today the opiates are widely recognized as excellent analgesics but with disadvantages that have impaired their use seriously. There is a clear need for a potent analgesic with minimal effects on the respiratory centers and gastrointestinal tract and preferably devoid of dependence liability. 213,99 €
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Technische Daten
Erscheinungsdatum
15.06.2013
Sprache
Englisch
EAN
9781489905871
Herausgeber
Springer US
Sonderedition
Nein
Autor
A.F. Casy, R.T. Parfitt
Seitenanzahl
518
Auflage
1
Einbandart
Broschiert
Buch Untertitel
Chemistry and Receptors
Schlagwörter
analgesics, biochemistry, chemistry, opioid, pharmacology, receptor, research
Thema-Inhalt
MKG - Pharmakologie
PSB - Biochemie
PSAN - Neurowissenschaften
PNR - Physikalische Chemie
Höhe
235 mm
Breite
15.5 cm
Transparenz & Sicherheit
Hersteller: Springer Nature Customer Service Center GmbH, Europaplatz 3, Heidelberg, Deutschland, 69115, ProductSafety@springernature.com
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