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Beschreibung
This book is a compendium of proceedings from the Symposium on Growth Hormone II: Basic and Clinical Aspects. The intent of the sym posium was to review current aspects of the rapidly expanding science of growth hormone (GH) neuroendocrinology, especially those develop ments that occurred since our last meeting in 1985. The meeting was timely since there have been many new and exciting… developments in basic research on the GH axis, and several new clinical applications for GH other than growth have been identified. For example, significant strides have been made into use of the bioengineered hormone as an anabolic in debilitated states and as an immunorestorative agent. Both these areas have received most attention as they relate to geriatric popu lations. Furthermore, recent focus on a novel family of GH secretagogues that complement the action of GHRH has shown that in animal models, these compounds have the potential to restore GH secretion in deficient or insufficient states, including growth retardation, obesity, and aging. Accordingly, these xenobiotics may have significant potential as drug products to stimulate physiological GH secretion and, thus, resist or reverse some of the maladaptive changes in form and function resulting from GH insufficiency. The importance of these agents as drug candidates is underscored by the diversity of molecules that have been studied by various pharmaceutical companies and the recent discovery that non peptide analogs with high oral bioavailability can be synthesized. 106,99 €
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Technische Daten
Erscheinungsdatum
18.10.2011
Sprache
Englisch
EAN
9781461383741
Herausgeber
Springer US
Serien- oder Bandtitel
Serono Symposia USA
Sonderedition
Nein
Seitenanzahl
379
Auflage
1
Einbandart
Broschiert
Buch Untertitel
Basic and Clinical Aspects
Schlagwörter
Immune System, Vivo, clinical application, glucocorticoids, molecular mechanisms, neuroendocrinology, regulation
Thema-Inhalt
PSAN - Neurowissenschaften
MFG - Physiologie
PSF - Zellbiologie (Zytologie)
PSV - Zoologie und Tierwissenschaften
Höhe
235 mm
Breite
15.5 cm
Transparenz & Sicherheit
Hersteller: Springer Nature Customer Service Center GmbH, Europaplatz 3, Heidelberg, Deutschland, 69115, ProductSafety@springernature.com
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