Technische Daten
Erscheinungsdatum
24.03.2022
Herausgeber
Springer International Publishing
Serien- oder Bandtitel
Topics in Medicinal Chemistry
Autorenporträt
Stefan Laufer is a Professor of Pharmaceutical/Medicinal Chemistry at Tuebingen University, Germany, and he had previously worked for 10 years in the Pharmaceutical Industry. His research interests are anti-inflammatory and cancer drug discovery with various eicosanoid (COX-1,2,3, LOXs, mPGES1, cPLA2) and protein kinase targets (p38, JAKs, JNKs, CK1d, mtEGRFs). Three compounds from his lab entered clinical development phases. Dr. Laufer chairs the ICEPHA (Interfaculty Center for Pharmacogenomics and Drug Research) and TüCADD, Tuebingen Center for Academic Drug Discovery. As part of this work, a proprietary kinase inhibitor collection is established (TüKIC, 10.000 cpds). He authored more than 500 publications, 14 books/bookchapters, and is inventor in 42 patent families.
Schlagwörter
ProteinKinase, Receptor Tyrosine Kinases, EGFR, VEGFR, PDGFR, Protein Kinase Inhibitors, Topology of Proteinkinases, c-met, MAP-Kinases
Thema-Inhalt
PNB - Medizinische Chemie, Pharmazeutische Chemie
PSB - Biochemie
PNN - Organische Chemie
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