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Bücher Englische Bücher Wissen & Bildung Naturwissenschaft, Medizin, Informatik, Technik Biologie Mikrobiologie Transmissible Spongiform Encephalopathies:
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Transmissible Spongiform Encephalopathies:
(Gebundene Ausgabe, Englisch)
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Beschreibung
In spite of a long history of intense investigation the transmissible spongiform encephalopathies remain a poorly understood family of neurodegenerative diseases. This group of diseases has been described in a wide variety of animal species and includes kuru, Creutzfeldt-Jakob disease, and Gerstmann-Straussler syndrome in humans, and scrapie, bovine spongiform encephalopathy, and related syndromes… in ruminants and rodents. In all cases spongiform degeneration and astrocytosis are seen in specimens of brain and a filterable transmissible agent is present in the brain and some other tissues of affected individuals. However, the precise nature of this agent remains unknown. Agent infectivity, which can so far only be assayed by serial transmission to new individuals, be remarkably resistant to inactivation has been shown to by heat, chemicals, and irradiation. These properties create significant biohazard possibilities during exposure to infected tissues. Transmission between humans was originally reco gnized in the unique epidemiology of kuru in New Guinea tribesmen, and concern about transmission from animals to humans has re-emerged as a result of the current epidemic of bovine spongiform encephalopathy in dairy cattle in Great Britain. Although interspecies transmission has often been achieved experimentally, its efficiency is highly variable. There fore, the possibility of spread of bovine spongiform encephalopathy from cattle to humans or various animal populations cannot be accurately predicted at this time. This volume presents a comprehensive update of know ledge concerning the transmissible spongiform encephalo pathies. Dieses Produkt haben wir gerade leider nicht auf Lager.
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Technische Daten
Erscheinungsdatum
29.11.1991
Sprache
Englisch
EAN
9783540538837
Herausgeber
Springer Berlin
Serien- oder Bandtitel
Current Topics in Microbiology and Immunology
Sonderedition
Nein
Seitenanzahl
288
Einbandart
Gebundene Ausgabe
Buch Untertitel
Scrapie, BSE and Related Human Disorders
Bandzählung
172
Schlagwörter
prion protein, Virologie, neurobiology, diseases, Neurobiologie, proteins, virology, tissue, Enzephalopathie, gene, protein, nucleic acid, Neurodegenerative Erkrankungen
Thema-Inhalt
MKFM - Mikrobiologie und Virologie
PSAN - Neurowissenschaften
MKFM - Mikrobiologie und Virologie
MJ - Klinische und Innere Medizin
PSF - Zellbiologie (Zytologie)
Höhe
235 mm
Breite
15.5 cm
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