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Bücher Englische Bücher Wissen & Bildung Naturwissenschaft, Medizin, Informatik, Technik Biologie Genetik & Gentechnik Roles of Skeletal Muscle in Organ Development
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Roles of Skeletal Muscle in Organ Development
(Broschiert, Englisch)
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Beschreibung
Muscle is the only tissue of the four basic types that make the body that can be completely ablated while allowing fetal survival. This book is a result of 25 years of research employing engineered mouse fetuses with no skeletal muscle, a model system that provides a unique opportunity to study body development holistically. A systematic anatomical analysis of such fetuses have shown that several… anatomical locations are affected by the absence of the skeletal muscle. This book contains a summarized description of affected anatomical locations such as the alveolar lung epithelium, motor neurons and giant pyramidal cells in the CNS, cholinergic amacrine cells of the retina, and type I hair cells of the crista ampullaris. Several specific bioinformatics and systems biology interventions are also described. The book provides an update on skeletal muscle development, musculoskeletal developmental interactions, trophic relationships between the skeletal muscle and the motor neurons, mechanics of lung development, functional development of two special senses, eye and ear, and finally, skeletal muscle-related reasons for human fetal akinesia and its consequences. This volume in the Advances in Anatomy, Embryology and Cell Biology series stresses the need to think about the developing body and its organs in terms of their mutual interdependence, and to think about diseases, such as pulmonary hypoplasia, amyotrophic lateral sclerosis, or cleft palate, in terms of that interdependence. Directed to developmental biologists, neuroscientists, tissue engineers and health professionals, this book exposes the ideas of interorgan communication and interdependence in homeostasis and disease. Dieses Produkt haben wir gerade leider nicht auf Lager.
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Technische Daten
Erscheinungsdatum
14.11.2023
Sprache
Englisch
EAN
9783031382147
Herausgeber
Springer International Publishing
Serien- oder Bandtitel
Advances in Anatomy, Embryology and Cell Biology
Sonderedition
Nein
Seitenanzahl
155
Einbandart
Broschiert
Buch Untertitel
Prenatal Interdependence among Cells, Tissues, and Organs
Schlagwörter
Skeletal muscle development, Skeletal muscle specific genes, Musculoskeletal development, prenatal development, lung development, ALS, mechanical forces in lung development, maintenance of motor neurons, musculoskeletal system development, functional cell differentiation, histology of the prenatal body, inter-organ communication, cleft palate, pulmonary hypoplasia, amyotrophic lateral sclerosis
Thema-Inhalt
PSC - Entwicklungsbiologie
MFC - Anatomie
Höhe
235 mm
Breite
15.5 cm
Hersteller: Springer, Europaplatz 3, Heidelberg, Deutschland, 69115, ProductSafety@springernature.com, Springer Nature Customer Service Center GmbH
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