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Bücher Englische Bücher Wissen & Bildung Naturwissenschaft, Medizin, Informatik, Technik Medizin Klinische Fächer Cancer Field Surgery in Gynecologic Oncology
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Cancer Field Surgery in Gynecologic Oncology
Michael Höckel, Rainer Kimmig, Ulrich Behn (Gebundene Ausgabe, Englisch)
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Beschreibung
This book encompasses the results of two decades of research on locoregional spread of gynecologic cancer, which put forth the ontogenetic cancer field model and its clinical translation in terms of ontogenetic tumor staging and cancer field surgery, particularly for carcinomas of the lower female genital tract. The ontogenetic cancer field model describes the propagation of malignant tumors… within distinct permissive tissue regions determined by the development of the tissue from which the neoplasm originated. As the morphogenesis of multicellular animals proceeds stepwise through bifurcational cell fate specification within tissue regions dictated by the positional identity and plasticity of the precursor cell populations, tumor formation during malignant progression occurs as a stepwise process in the reverse direction with regard to positional identity and plasticity. This principle of order can be exploited for diagnosis, treatment and prognosis of cancer in general. The motivation to study in depth the topography of tumor spread arose from the insight that the conventional view of local cancer propagation as an unlimited isotropic process is falsified by numerous inconsistencies with clinical facts. Consequently, conventional cancer therapy based on this model cannot achieve optimal outcomes. The cancer field model and its application in gynecologic oncology has been published in highly ranked journals. However, the complexity of the principles and practice need the format of a well-structured book for their successful transmission to gynecologic surgeons, clinical oncologists, cancer researchers and postgraduate medical students. Dieses Produkt haben wir gerade leider nicht auf Lager.
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Technische Daten
Erscheinungsdatum
12.04.2025
Sprache
Englisch
EAN
9783031830297
Herausgeber
Springer International Publishing
Sonderedition
Nein
Autor
Michael Höckel, Rainer Kimmig, Ulrich Behn
Seitenanzahl
270
Einbandart
Gebundene Ausgabe
Buch Untertitel
Principles and Practice
Schlagwörter
Morphogenesis, Human development, Female differentiation, Positional identity, Transdetermination, Tissue borders, Local tumor spread, Regional tumor spread, Cancer progression
Thema-Inhalt
MJCL - Onkologie
MKC - Gynäkologie und Geburtshilfe
MN - Chirurgie
Höhe
254 mm
Breite
17.8 cm
Hersteller: Springer, Europaplatz 3, Heidelberg, Deutschland, 69115, ProductSafety@springernature.com, Springer Nature Customer Service Center GmbH
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