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- Startseite
Bücher Englische Bücher Wissen & Bildung Naturwissenschaft, Medizin, Informatik, Technik Biologie Genetik & Gentechnik Genes, Environments and Interactions
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Genes, Environments and Interactions
José M Álvarez-Castro (Broschiert, Englisch)
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Beschreibung
Genetic effects are the core concepts from which quantitative genetics and the evolutionary synthesis emerged. The groundbreaking theory of genetic effects was first proposed over a century ago. This book revises that theory, both conceptually and mathematically, and brings it up-to-date. The theory here compiled is supplemented with non-previously-published developments covering the broadest… spectrum of simultaneously multiallelic and multilocus architectures with autosomal and sex-linked loci Arbitrary interactions (dominance, gene-gene, gene-environment, gene-sex, and parent-of-origin interactions) are accounted for Both effects of allele substitutions from the reference of individual genotypes and in the context of populations are worked out Populations are considered regardless of any departures from equilibrium frequencies (including both departures from Hardy-Weinberg, departures from linkage equilibrium, and non-random associationsbetween/among genes and environments) All developments are derived under the same mathematical framework, so that transformations of genetic effects between different contexts are easily allowed In brief, this book enables novel applications to current empirical paradigms (like gene-mapping and genomic prediction) while adhering to the classical conceptualization of genetic effects and variance decomposition that let quantitative genetics and the evolutionary synthesis flourish. All relevant concepts are carefully clarified and discussed from a historical perspective. The theoretical developments presented in the book are illustrated by built-in cases and applications with real data. Reassuringly, the adequacy of the theory here presented is corroborated based on the fundamentals of model development. Dieses Produkt haben wir gerade leider nicht auf Lager.
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Technische Daten
Erscheinungsdatum
19.01.2025
Sprache
Englisch
EAN
9783031411618
Herausgeber
Springer International Publishing
Sonderedition
Nein
Autor
José M Álvarez-Castro
Seitenanzahl
224
Einbandart
Broschiert
Buch Untertitel
Evolutionary and Quantitative Genetics Brought Up-to-date
Schlagwörter
Quantitative genetics, Evolutionary genetics, Models of genetic effects, Gene interaction, Gene-environment interaction, Gene mapping, genomic selection
Thema-Inhalt
PSAK - Genetik (nicht-medizinisch)
PSAJ - Evolution
PSAX - DV-gestützte Biologie/Bioinformatik
Höhe
235 mm
Breite
15.5 cm
Hersteller: Palgrave Macmillan, Europaplatz 3, Heidelberg, Deutschland, 69115, ProductSafety@springernature.com, Springer Nature Customer Service Center GmbH
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