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Bücher Englische Bücher Wissen & Bildung Naturwissenschaft, Medizin, Informatik, Technik Chemie Pharmaceutical Salts
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Beschreibung
About half of all drugs used in medicine are administered as salts, and the formation and the selection of a suitable salt for a drug candidate is an essential step in the preclinical phase of drug development. Surprisingly, however, the scientific literature on this topic is rather limited and scattered throughout numerous journals and patents. The majority of medicinal chemists in pharmaceutical… industry whose primary focus is the design and synthesis of novel compounds as future drug entities are organic chemists for whom salt formation is often a marginal activity restricted to the short-term objective of obtaining crystalline material, and, because a comprehensive resource that addresses the preparation, selection, and use of pharmaceutically active salts has not been available, may forego the opportunities for increased efficacy and improved drug delivery provided by selection of an optimal salt. To fill this gap in the pharmaceutical bibliography, we have gathered an international team of seventeen authors from academia and pharmaceutical industry who, in their contributions to this volume, present the necessary theoretical foundations as well as a wealth of detailed practical experience in the choice of pharmaceutically active salts.
Altogether, the contributions in this book reflect the multidisciplinary nature of the science involved in selection of suitable salt forms for new drug products. The editors have taken care to address every conceivable aspect of the preparation of pharmaceutical salts. This book is destined to be an essential reference for students of medicinal and pharmaceutical chemistry, and an indispensable handbook for research-and-development chemists, analytical chemists, biologists, development pharmacists, regulatory and patent specialists, and medicinal scientists engaged in preclinical development of drugs. This comprehensive up-to-date guide will be an instructive companion for all scientists involved in research and development of drugs and, in particular, of pharmaceutical dosage forms. Dieses Produkt haben wir gerade leider nicht auf Lager.
Handgeprüfte Gebrauchtware
Bis zu 50 % günstiger als neu
Der Umwelt zuliebe
Technische Daten
Erscheinungsdatum
15.12.2001
Sprache
Englisch
EAN
9783906390260
Herausgeber
Helvetica Chimica Acta
Sonderedition
Nein
Seitenanzahl
374
Auflage
1
Einbandart
Gebundene Ausgabe
Buch Untertitel
Properties, Selection and Use
Schlagwörter
Arzneimittel, Pharmazeutische Chemie, Medizin, Pharmazie / Pharmazie, Pharmakologie, Toxikologie, Salz
Höhe
246 mm
Breite
18 cm
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