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Bücher Englische Bücher Wissen & Bildung Naturwissenschaft, Medizin, Informatik, Technik Chemie Pharmaceutical Salts
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Beschreibung
The first edition of this handbook was a tremendous success, collating the scientific literature on this topic that had otherwise been rather limited and scattered throughout numerous journals and patents. The result was a comprehensive resource that addresses the preparation, selection, and use of pharmaceutically active salts, examining the opportunities for increased efficacy and improved drug… delivery provided by the selection of an optimal salt. This second, revised edition is designed to meet the continued interest in both the topic and the book.
Altogether, the contributions to this book by international team of authors from academia and pharmaceutical industry reflect the multidisciplinary nature of the science involved in selection of suitable salt forms for new drug products. They present the necessary theoretical foundations as well as a wealth of detailed practical experience in the choice of pharmaceutically active salts, taking great care to address every conceivable aspect of the preparation of pharmaceutical salts.
An introductory chapter presents a concise review of the various objectives in the pursuit of pharmaceutically active salts, followed by the theoretical background of salt formation. There then follow chapters on the practice of salt formation in an industrial R&D environment, as well as regulatory and patent issues. Practical examples for the practitioners at the lab bench are provided, before the book concludes with a comprehensive annotated compilation of the individual salt-forming acids and bases with their relevant properties, followed by an appendix containing tables with the acids and bases sorted alphabetically and by pKa, supplemented with other useful facts and data.
An essential reference for students of medicinal and pharmaceutical chemistry, and an indispensable handbook for R&D chemists, analytical chemists, biologists, development pharmacists, regulatory and patent specialists, and medicinal scientists engaged in preclinical development of drugs. In addition, this comprehensive and up-to-date guide is an instructive companion for all scientists involved in the research and development of drugs and, in particular, of pharmaceutical dosage forms. Dieses Produkt haben wir gerade leider nicht auf Lager.
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Technische Daten
Erscheinungsdatum
18.03.2011
Sprache
Englisch
Originalsprache
Englisch
EAN
9783906390512
Herausgeber
Helvetica Chimica Acta
Sonderedition
Nein
Seitenanzahl
374
Auflage
2
Einbandart
Gebundene Ausgabe
Buch Untertitel
Properties, Selection, and Use
Schlagwörter
Anorganische Chemie, Arzneimittel, Chemie, Chemistry, Drug Formulation & Delivery, Inorganic Chemistry, Pharmazeutische Chemie, Salz, Wirkstoffformulierung, Wirkstofftransport
Thema-Inhalt
PNB - Medizinische Chemie, Pharmazeutische Chemie
Höhe
246 mm
Breite
18 cm
-.-
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