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Beschreibung
Prion Protein Protocols brings together a collection of current protocols in the field of mammalian prion disease research. Since identification of the prion protein gene some 20 years ago, what were once thought to be rare, neurodegenerative diseases of humans and animals have become a major research area. The major interest in this field results from the epidemic of bovine spongiform… encephalopathy and the subsequent human prion disease, variant Creutzfeldt–Jakob disease, which still poses an unknown risk to human health. The “unknowns” in the field stem from the enigmatic nature of infectious prions, the infectious agent that can transmit these diseases between individuals. Although much information has been gained over the past two decades about the molecular nature of prion proteins, only very recently have several research groups begun to cast light on how to turn the normal prion protein into its aberrant, infectious form. Prion Protein Protocols brings together a collection of protocols from 13 diff- ent laboratories in five countries covering basic science and diagnostic areas of prion research. Together, the chapters provide an up-to-date collection of current methods in this unique area of neuroscience. The notes section at the end of each methods chapter provides useful insight into the experimental techniques, and they are no doubt a benefit to researchers wanting to use these technologies. 106,99 €
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Technische Daten
Erscheinungsdatum
10.12.2010
Sprache
Englisch
EAN
9781617378317
Herausgeber
Humana Press
Serien- oder Bandtitel
Methods in Molecular Biology
Sonderedition
Nein
Seitenanzahl
280
Auflage
1
Einbandart
Taschenbuch
Bandzählung
459
Schlagwörter
Bovine Spongiform Encepalopathy, Creutzfeldt-Jakob Disease, Infectious prions, Mammalian prion disease, Neuroscience, Protein misfolding, Rapid bioassay, cell lines, infection, infectious, molecular biology, neurons, infectious diseases
Thema-Inhalt
PSAN - Neurowissenschaften
PSB - Biochemie
MJC - Krankheiten und Störungen
PSF - Zellbiologie (Zytologie)
Höhe
235 mm
Breite
15.5 cm
Transparenz & Sicherheit
Hersteller: Humana, Europaplatz 3, Heidelberg, Deutschland, 69115, ProductSafety@springernature.com, Springer Nature Customer Service Center GmbH
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