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Greene's Protective Groups in Organic Synthesis
Peter G. M. Wuts (Gebundene Ausgabe, Englisch)
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Beschreibung
The Most Comprehensive Guide to Protective Groups in Organic Synthesis Currently Available
For more than twenty-five years, Protective Groups in Organic Synthesis has been the definitive guide for organic chemists in designing synthetic routes. Now in its fourth edition, the text continues to be a uniquely comprehensive and an indispensable reference for both synthetic organic and medicinal Dieses Produkt haben wir gerade leider nicht auf Lager.
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Technische Daten
Erscheinungsdatum
08.12.2006
Sprache
Englisch
EAN
9780471697541
Herausgeber
John Wiley & Sons
Sonderedition
Nein
Autor
Peter G. M. Wuts
Seitenanzahl
1110
Auflage
4
Einbandart
Gebundene Ausgabe
Autorenporträt
PETER G. M. WUTS, PHD, is a Senior Research Fellow at Pfizer in Ann Arbor, Michigan.
The late THEODORA W. GREENE, PHD, was the librarian for the Rowland Institute for Science and former assistant editor for Organic Syntheses.
Schlagwörter
Organische Chemie, Schutzgruppen (Chem.), Organische Synthese
Inhaltsverzeichnis
Preface to the Fourth Edition.
Preface to the Third Edition.
Preface to the Second Edition.
Preface to the First Edition.
Abbreviations.
1. The Role of Protective Groups in Organic Synthesis.
2. Protection for the Hydroxyl Group, Including 1,2- and 1,3-Diols.
Ethers.
Esters.
Protection for 1,2- and 1,3-Diols.
3. Protection for Phenols and Catechols.
Protection for Phenols.
Ethers.
Silyl Ethers.
Esters.
Carbonates.
Aryl Carbamates.
Phosphinates.
Sulfonates.
Protection for Catechols.
Cyclic Acetals and Ketals.
Cyclic Esters.
Protection for 2-Hydroxybenzenethiols.
4. Protection for the Carbonyl Group.
Acetals and Ketals.
Miscellaneous Derivatives.
Monoprotection of Dicarbonyl Compounds.
5. Protection for the Carboxyl Group.
Esters.
Amides and Hydrazides.
Protection of Boronic Acids.
Protection of Sulfonic Acids.
6. Protection for the Thiol Group.
Thioethers.
Thioesters.
Miscellaneous Derivatives.
7. Protection for the Amino Group.
Carbamates.
Amides.
Special --NH Protective Groups.
Protection for Imidazoles, Pyrroles, Indoles, and other Aromatic Heterocycles.
Protection for the Amide --NH.
Protection for the Sulfonamide --NH.
8. Protection for the Alkyne --CH.
9. Protection for the Phosphate Group.
Some General Methods for Phosphate Ester Formation.
Removal of Protective Groups from Phosphorus.
Alkyl Phosphates.
Phosphates Cleaved by Cyclodeesterifi cation.
Benzyl Phosphates.
Phenyl Phosphates.
Photochemically Cleaved Phosphate Protective Groups.
Amidates.
Miscellaneous Derivatives.
10. Reactivities, Reagents, and Reactivity Charts.
Reactivities.
Reagents.
Reactivity Charts.
1 Protection for the Hydroxyl Group: Ethers.
2 Protection for the Hydroxyl Group: Esters.
3 Protection for 1,2- and 1,3-Diols.
4 Protection for Phenols and Catechols.
5 Protection for the Carbonyl Group.
6 Protection for the Carboxyl Group.
7 Protection for the Thiol Group.
8 Protection for the Amino Group: Carbamates.
9 Protection for the Amino Group: Amides.
10 Protection for the Amino Group: Special --NH Protective Groups.
11 Selective Deprotection of Silyl Ethers.
Index.
Höhe
243 mm
Breite
16.5 cm
-.-
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